News & Insights

Research publications, platform milestones, press releases, technical resources, and thought leadership from Constructive Bio.

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As featured in
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News, Updates &
Media Coverage

Company announcements, scientific updates, press releases, and external media coverage.

White Papers

In-depth technical briefs, platform insights, and thought leadership for partners and researchers.

Scientific Publications

Published research underpinning the Constructive Bio platform — from fundamental genetic code expansion to scalable biomanufacturing.

Syn57: E. coli Engineered with the Most Compressed Genetic Code Ever Created, Freeing Seven Codons for ncAA Incorporation

Syn57 dramatically expands the ‘codon space’ available for non-canonical amino acid incorporation, from three freed codons in Syn61 to seven…

Genetic Code-Locking Gives Recoded Organisms Stable Virus Resistance, Eliminating a Key Biomanufacturing Risk

Viral contamination is a major cost and quality risk in biomanufacturing. Phage infection can wipe out an entire production run,…

Automated Orthogonal tRNA Generation Removes a Key Bottleneck in Scaling Non-Canonical Amino Acid Incorporation

Speed matters in drug development. Automating tRNA generation means Constructive Bio can rapidly create the molecular machinery needed to incorporate…

Non-Canonical
Amino Acid Database

The chemical alphabet of the Constructive Bio platform. Each ncAA is a molecular capability — a building block for engineering protein function beyond nature.

From our LinkedIn

Latest updates, news, and conversations from the Constructive Bio team.