Nature Biotechnology Editor’s Pick on Constructive Bio

We’re honoured that Nature Biotechnology has selected Constructive Bio as one of its 2025 Editor’s Picks — recognising pioneering companies shaping the future of biotechnology.

The article highlights how our work builds on decades of research led by our co-founder and CSO, Prof. Jason Chin, at the MRC Laboratory of Molecular Biology. His team’s creation of synthetic E. coli with rewritten genomes laid the groundwork for programmable organisms capable of producing new classes of proteins and polymers.

At Constructive Bio, we’re transforming that scientific foundation into real-world applications — from biomanufacturing sustainable materials to developing next-generation therapeutics. By encoding non-canonical amino acids into proteins, we can expand nature’s chemistry to design molecules that biology has never seen before.

Our CEO, Dr Ola Wlodek, told Nature Biotechnology: “You can harness the ribosome as the ultimate high-fidelity engine for making new products.” This vision drives everything we do — using the scalability of life to build a cleaner, smarter, and more capable biomanufacturing future.

You can read the full Nature Biotechnology feature here:

https://www.nature.com/articles/s41587-025-02850-2