Publications
Our groundbreaking research published in the world's leading scientific journals.
Sense codon reassignment enables viral resistance and encoded polymer synthesis
Robertson, W.E., Funke, L.F.H., de la Torre, D., Fredens, J., Elliott, T.S., Spinck, M., Christova, Y., Cervettini, D., Böge, F.L., Liu, K.C., Buse, S., Maslen, S., Salmond, G.P.C., Chin, J.W. Science 372(6546), 1057–1062 (2021)
Key publications
Total synthesis of Escherichia coli with a recoded genome
Fredens, J., Wang, K., de la Torre, D., Funke, L.F.H., Robertson, W.E., Christova, Y., Chia, T., Schmied, W.H., Dunkelmann, D.L., Beránek, V., Uttamapinant, C., Gonzalez Llamazares, A., Elliott, T.S., Chin, J.W.
Nature 569(7757), 514–518 (2019)
Read paper ↗Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids
Dunkelmann, D.L., Willis, J.C.W., Beattie, A.T., Chin, J.W.
Nature Chemistry 12(6), 535–544 (2020)
Read paper ↗White papers
The Genome Synthesis Revolution
The Genome Synthesis Revolution
Reprogramming Life
Reprogramming Life
Programmable biomolecules of the future
Programmable biomolecules of the future
2025 Non-Canonical Amino Acid Advent Calendar
Bringing together all of December 2025's non-canonical Advent calendars.
Selected publications
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles
Spinck, M., Piedrafita, C., Robertson, W.E., Elliott, T.S., Cervettini, D., de la Torre, D., Chin, J.W.
Nature Chemistry 15(1), 61–69 (2023)
Read paper ↗Refactored genetic codes enable bidirectional genetic isolation
Zürcher, J.F., Robertson, W.E., Kappes, T., Petris, G., Elliott, T.S., Salmond, G.P.C., Chin, J.W
Science
Read paper ↗Sense codon reassignment enables viral resistance and encoded polymer synthesis
Robertson, W.E., Funke, L.F.H., de la Torre, D., Fredens, J., Elliott, T.S., Spinck, M., Christova, Y., Cervettini, D., Böge, F.L., Liu, K.C., Buse, S., Maslen, S., Salmond, G.P.C., Chin, J.W.
Science 372(6546), 1057–1062 (2021)
Read paper ↗Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids
Dunkelmann, D.L., Willis, J.C.W., Beattie, A.T., Chin, J.W.
Nature Chemistry 12(6), 535–544 (2020)
Read paper ↗