REXER and GENESIS: The Genome Writing Toolkit for Creating Custom Synthetic Genomes in E. coli

April 1, 2021
Robertson, W.E., Funke, L.F.H., de la Torre, D., Fredens, J., Wang, K., Chin, J.W.
Nature Protocols 16, 2345 (2021)

Why it matters

REXER and GENESIS are the 'how' behind Constructive Bio's genome synthesis capability. They enable the precise, large-scale rewriting of bacterial genomes that produces the company's recoded production organisms. Having a published, validated protocol in Nature Protocols demonstrates the robustness and reproducibility of the approach that underpins the BioForge platform.